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Mol Cell Proteomics. 2012 Dec; 11(12): 1790–1800.Published online 2012 Sep 13. doi: 10.1074/mcp.M112.020800PMCID: PMC3518105PMID: 22984286 High-resolution Mapping of Linear Antibody Epitopes Using Ultrahigh-density Peptide Microarrays*  Søren Buus,‡§¶ Johan Rockberg,§‖ Björn Forsström,‖ Peter Nilsson,** Mathias Uhlen,‖** andClaus Schafer-Nielsen¶‡‡§§Author information Article notes Copyright and License information DisclaimerThis article has been cited by other articles in PMC.  Associated Data Supplementary Materials Supplementary informationsupp_11_12_1790__index.html (1021 bytes)supp_M112.020800_mcp.M112.020800-1.pdf (442K) Go to: Abstract Antibodies empower numerous important scientific, […]

Identification and Mapping of Linear Antibody Epitopes in Human Serum Albumin Using High-Density Peptide Arrays Lajla Bruntse Hansen, Soren Buus , Claus Schafer-Nielsen    Published: July 23, 2013 https://doi.org/10.1371/journal.pone.0068902   Article Authors Metrics Comments Media Coverage Abstract Introduction Methods Results Discussion Supporting Information Author Contributions References Reader Comments (0) Media Coverage (0) Figures   Abstract We have

Towards High-throughput Immunomics for Infectious Diseases: Use of Next-generation Peptide Microarrays for Rapid Discovery and Mapping of Antigenic Determinants Santiago J. Carmona, Morten Nielsen, Claus Schafer-Nielsen, Juan Mucci, Jaime Altcheh, Virginia Balouz, Valeria Tekiel, Alberto C. Frasch, Oscar Campetella, Carlos A. Buscaglia and Fernán AgüeroMolecular & Cellular Proteomics July 1, 2015, First published on April 28, 2015, 14 (7) 1871-1884; https://doi.org/10.1074/mcp.M114.045906   Article Figures & Data Info & Metrics eLetters  PDF   Abstract Complete

Identifying protective Streptococcus pyogenesvaccine antigens recognized by both B and T cells in human adults and children Rasmus Mortensen , Thomas Nørrelykke Nissen , Sine Fredslund , Ida Rosenkrands , Jan Pravsgaard Christensen , Peter Andersen  & Jes Dietrich Scientific Reports volume6, Article number: 22030 (2016) | Download Citation Abstract No commercial vaccine exists against Group A streptococci (GAS; Streptococcus pyogenes) and only little is known about

High-density peptide array analysis service We offer a complete service in which we synthesize the High-density peptide arrays , incubate them with your ligand, record the results and send you the recorded images + raw data together with relevant analytical conclusions (e.g. epitope peptides and single-residue epitope mappings). If you have access to suitable recording equipment (array-scanner, fluorescence microscope, SPRi-device

High-density peptide array analysis service We offer a complete service in which we synthesize the High-density peptide arrays , incubate them with your ligand, record the results and send you the recorded images + raw data together with relevant analytical conclusions (e.g. epitope peptides and single-residue epitope mappings). If you have access to suitable recording equipment (array-scanner, fluorescence microscope, SPRi-device

High-density peptide microarrays We have developed a complete set of tools for design, synthesis and recording of high-density peptide microarrays [1-3]. The arrays can contain up to 2 million predefined peptide sequences and they are well suited for identification of antibody peptide epitopes and for mapping of peptide recognition motifs for other proteins (receptor ligands, protein kinases etc.). Work on the high-density peptide microarrays was initiated

Peptide synthesis ordering The price for custom peptides depends not only on the length of their sequence and the desired amount and purity. The amino acid sequence of the peptide is much more important in the calculations of price. With some relatively short peptides the aggregation tendency during synthesis and/or purification is so high that

Peptide synthesis and handling The physico-chemical properties of peptides are heavily dependent on their amino acid sequence. Synthesis of the peptides most often proceed smoothly, and it is in the workup steps most problems with handling of the peptides are encountered. In solid phase peptide synthesis using the Fmoc-strategy, cleavage of side chain protection groups and

Peptide modifications We provide purified custom peptides with an extensive range of modifications. Listed below is a range of the more common modifications. This list is by no means exhaustive and we will be happy to quote on synthesis of peptides with more specialized modifications. Some of the modifications can be also be applied to